Highlands Oncology Site Profile


Highlands Oncology is a leading cancer center in northwest Arkansas, providing care to over 12,000 patients from many different states in the region. They have been participating in clinical trials for over 20 years, and their Research Department runs numerous trials in both oncology and hematology. These trials are designed to compare new experimental medications and treatments to existing options in order to advance cancer care for patients around the world. Highlands Oncology is also the only community-based Phase I oncology clinical trial center in the state of Arkansas. With help from their Research Department and clinical trials, they stay at the cutting edge of technology, ensuring they can offer the latest treatments and improved outcomes to their patients. They are committed to advancing cancer care and hope to continue to be a leader in the field. With multidisciplinary cancer teams, highly advanced treatment options, and industry leading clinical studies, Highlands Oncology Group offers nationally recognized cancer care right here in northwest Arkansas.

Quick Facts

Region Quick Facts

  • 49.9% Female (50.92% Arkansas)
  • 62.45% White, 17.89% Hispanic/Latino (77.31% White, 7.16% Hispanic/Latino Arkansas)
  • 13% uninsured (10.64% Arkansas)
Little Rock6.62%17.02%8.59%14.46%13.06%12.7%14.7%

Impeccable success in conducting clinical trials can be attributed to the following, and more.

  • Robust research department comprised of over 30 research specialists
  • Three cancer centers, each equipped with consenting, imaging, and pharmacy capabilities
  • Major research center at Springdale location
  • Integration with primary clinical staff, such as universal pre-screening for clinical trial inclusion
  • Host site for multiple multidisciplinary tumor boards, enhancing opportunities for patient identification and subsequent enrollment from a wider network
  • Only community based Phase I oncology clinical trial center in the state of Arkansas

Health Outcomes

  • Cancer is the second leading cause of death in Arkansas
  • Arkansas amongst five states with the highest age-adjusted lung cancer death rates per 100,000

Highlands Oncology is a premier destination for clinical research, offering the following:

  • Highly trained dedicated research department, with ICH/GCP and human subject protection training certifications
  • EMR-integrated and AI-driven research tools for patient screening
  • Timely tissue biopsy processing, due to partnership with local hospitals and pathology associates
  • Dedicated clinical research pharmacist
  • Remote and on-site monitoring capabilities
  • In-house support for research budgets and contracts
  • Standardized lab ranges at all three locations, with capacity to send out to LabCorp or Northwest Arkansas Pathology Associates for additional research
  • Central and local IRB facilitation, with central preferred
  • Dedicated primary Research Data Coordinator assigned to each study

The hospital possesses clinical and research equipment such as:

  • MRI
  • PET/CT
    • Fluciclovine F18
    • Copper Cu64 dotatate
    • Fluorodeoxyglucose
    • Sodium fluoride
    • Ga68 gozetotide
    • F18 piflufolastat 
  • Ultrasound
  • X-ray 
  • Other scans in partnership with local hospitals:
    • Whole body bone scans using technetium-99m
    • Multigated acquisition (MUGA) scans
  • Research pharmacy in Springdale with SmartSense temperature technology
    • Ambient and refrigerated centrifuges
    • -20°C and -80°C freezers available for sample storage
  • Monitored, entry-limited USP 800-compliant storage rooms with back-up generators
  • Screening, diagnostics, imaging, labs and surgery located within one single integrated facility

A spotlight at some of the hospital’s amenities:

  • Total of 67 exam rooms, 6 procedure rooms, 106 treatment chairs, and 4 shot chairs among three locations
    • Two exam rooms reserved for research subjects


  • 10 on-site monitoring stations with computer, printer, copier, scanner, a phone, and Wi-Fi
  • Software licenses include: Ambra, Deep Lens, Florence, DocuSign, OncoEMR, OncoTrials, Velos, and Vestigo

Research Staff

Helen Holtzen
MS, RN, Director of Research Bio
Adam Torres
BSBA, BSN, RN, CCRP, Assistant Director of Research Bio

Clinical Procedures Capacity:

The system is clinically capable to perform a wide variety of surgeries and procedures which include:

Transcatheter Aortic Valve Replacement
Mini MVR
Coronary Artery Bypass Grafting Surgery (CABG)
Video Assisted Thoracoscopic Surgery (VATS)
Tricuspid Valve Repair or Replacement (MVR)
Alcohol septal ablation
Diaphragm Plication
Ascending Aortic Aneurysm Repair
EP studies
Endovascular Abdominal Aortic Aneurysm Repair
Left Atrial Appendage Clip or Resection
Thoracic Endovascular Aortic Aneurysm Repair
Surgical Ablation (MAZE)
Epicardial ablation
Carotid Endarterectomy
Minimally Invasive Cardiac Surgery
Temporary pacemaker
Peripheral Bypass Grafting Surgery
PFO, PDA, ASD, and VSD correction
Permanent pacemaker
Open Abdominal Aneurysm surgery
Gastric bypass
Internal cardiac defibrillators
Aortobifemoral Bypass Grafting Surgery
Lead extraction
Aortobifemoral Bypass Grafting Surgery
Peripheral amputation
Cryoplasty therapy
Coronary Artery Bypass Grafting Surgery (CABG)
Diamondback 360
Watchman device
Aortic Valve Replacement (AVR)
Laser Atherectomy
Mini AVR
Peripheral Stenting
Mitral Valve Repair or Replacement (MVR)
SilverHawk Plaque Excision System
Thrombolytic therapy
Alcohol septal ablation
EP studies